Ernesto Fedele

(+39) 010 3532659

Ernesto Fedele


Pharmacology and Toxicology

Description of activity in the organization

Studies on CNS neurotransmission including:

  • Pharmacological characterization of presynatic receptor types and subtypes
  • Exocytotic and non exocytotic mechanisms of neurotransmitter release
  • In vivo studies on neurotransmitter release and cGMP and cAMP production by intracerebral microdialysis
  • Alterations of neurotransmission in multiple sclerosis and autism
  • Functional characterization of selective PDE4D inhibitors for Alzheimer’s Disease
  • Production of Aβ and its physiological role


Publications list