Di seguito troverete le principali pubblicazioni per ogni unità operative.
Per visualizzare l'elenco completo consulta l'archivio IRIS

Biochimica

  1. Stifanese R, Averna M, De Tullio R, Pedrazzi M, Beccaria F, Salamino F, Milanese M, Bonanno G, Pontremoli S, Melloni E. Adaptive modifications in the calpain/calpastatin system in brain cells after persistent alteration in Ca2+ homeostasis. J Biol Chem. 2010 285:631-43. PMID: 19880516
  2. Roperto S, De Tullio R, Raso C, Stifanese R, Russo V, Gaspari M, Borzacchiello G, Averna M, Paciello O, Cuda , Roperto F. Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of the urinary bladder in cattle. PLoS One. 2010 5:e10299. PMID: 20421977
  3. HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration. Bassi R, Giussani P, Anelli V, Colleoni T, Pedrazzi M, Patrone M, Viani P, Sparatore B, Melloni E, Riboni L. J Neurooncol. 2008 87:23-33 PMID: 17975708

Biologia Strutturale e Cellulare

  1. Bruzzone S, Moreschi I, Usai C, Guida L, Damonte G, Salis A, Scarfì S, Millo E, De Flora A, Zocchi E. Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger. Proc Natl Acad Sci USA. 2007 Apr 3;104(14):5759-64. Epub 2007 Mar 26. PMID:17389374
  2. Scapolla C, Cangemi G, Barco S, Barbagallo L, Bugnone D, Maffia A, Melioli G,Profumo A, Benatti U, Damonte G. Identification and structural characterization by LC-ESI-IONTRAP and LC-ESI-TOF of some metabolic conjugation products of homovanillic acid in urine of neuroblastoma patients. J Mass Spectrom. 2012, Jul;47(7):816-24.PMID: 22791248.
  3. De Castro C, Molinaro A, Piacente F, Gurnon JR, Sturiale L, Palmigiano A, Lanzetta R, Parrilli M, Garozzo D, Tonetti MG, Van Etten JL. Structure of N-linked oligosaccharides attached to chlorovirus PBCV-1 major capsid protein reveals unusual class of complex N-glycans. Proc Natl Acad Sci U S A. 2013, 20;110(34):13956- PMID: 23918378
  4. Magnone M, Ameri P, Salis A, Andraghetti G, Emionite L, Murialdo G, De Flora A, Zocchi E. Microgram amounts of abscisic acid in fruit extracts improve glucose tolerance and reduce insulinemia in rats and in humans. FASEB J. 2015 Aug 4. pii: fj.15-277731. [Epub ahead of print]. PMID: 26243865

Farmacologia e Tossicologia

  1. Milanese M, Giribaldi F, Melone M, Bonifacino T, Musante I, Carminati E, Rossi P.I.A., Vergani L, Voci A, Conti F, Puliti A, Bonanno G. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis. Neurobiol Dis. 2014; 64:48-59. PMID: 24361555
  2. Ricciarelli R, Puzzo D, Bruno O, Canepa E, Gardella E, Rivera D, Privitera L, Domenicotti C, Marengo B, Marinari UM, Palmeri A, Pronzato MA, Arancio O, Fedele E. A novel mechanism for cAMP-mediated memory formation: role of amyloid Ann Neurol 2014; 75:602-607. PMID: 24591104
  3. Di Prisco S, Merega E, Milanese M, Summa M, Casazza S, Raffaghello L, Pistoia V, Uccelli A, Pittaluga A. CCL5-Glutamate interaction in central nervous system: early and acute  presynaptic defects in EAE mice. Neuropharmacology 2013; 75:337-46. PMID:23958452

Immunologia Clinica

  1. Parodi A., Traverso P., Kalli F., Conteduca G., Tardito S, Curto M, Grillo F, Mastracci L, Bernardi C, Nasi G, Minaglia F, Simonato A, Carmignani G, Ferrera F, Fenoglio D, Filaci G. Residual tumor micro-foci and overwhelming regulatory T lymphocyte infiltration are the causes of bladder cancer recurrence. - Oncotarget. 2016 Jan 25. doi: 10.18632/oncotarget.7024.
  2. Dentone C, Di Biagio A, Parodi A, Bozzano F, Fraccaro P, Signori A, Cenderello G, Mantia E, Orofino G, De Maria A, Filaci G, Fenoglio D. Innate immunity cell activation in virologically suppressed HIV-infected maraviroc-treated patients.AIDS. 2014 Apr 24;28(7):1071-4. doi: 10.1097/QAD.0000000000000194.PMID:24499952
  3. Fenoglio D, Traverso P, Parodi A, Tomasello L, Negrini S, Kalli F, Battaglia F, Ferrera F, Sciallero S, Murdaca G, Setti M, Sobrero A, Boccardo F, Cittadini G, Puppo F, Criscuolo D, Carmignani G, Indiveri F, Filaci G. A multi-peptide, dual-adjuvant telomerase vaccine (GX301) is highly immunogenic in patients with prostate and renal cancer. Cancer Immunol Immunother. 2013 Jun;62(6):1041-52. doi: 10.1007/s00262-013-1415-9. Epub 2013 Apr 17.PMID:23591981
  4. Parodi A, Battaglia F, Kalli F, Ferrera F, Conteduca G, Tardito S, Stringara S, Ivaldi F, Negrini S, Borgonovo G, Simonato A, Traverso P, Carmignani G, Fenoglio D, Filaci G. CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes. Cancer Immunol Immunother. 2013 May;62(5):851-62. doi: 10.1007/s00262-013-1392-z. Epub 2013 Jan 29.PMID:23359087

Immunologia Molecolare

  1. Bozzano F, Marras F, Ascierto ML, Cantoni C, Cenderello G, Dentone C, Di Biagio A, Orofino G, Mantia E, Boni S, De Leo P, Picciotto A, Braido F, Antonini F, Wang E, Marincola F, Moretta L, De Maria A. “Emergency exit” of bone-marrow-resident CD34+DNAM-1brightCXCR4+ committed lymphoid precursors during chronic infection and inflammation supports innate and adaptive immune responses. Nature Communications. Nat Commun. 2015 Oct 5;6:8109. doi: 10.1038/ncomms9109.
  2. Ascierto ML, Bozzano F, Bedognetti D, Marras F, Schechterly C, Matsuura K, Picciotto A, Marenco S, Zhao Y, DeGiorgi V, Sommariva M, Moretta L, Wang E, Alter HJ, Marincola FM, De Maria A. Inherent transcriptional signatures of NK cells are associated with response to IFNα + rivabirin therapy in patients with Hepatitis C Virus. J Transl Med. 2015 Mar 1;13(1):77.
  3. Marras F, Nicco E, Bozzano F, Di Biagio A, Dentone C, Pontali E, Boni S, Setti M, Orofino G, Mantia E, Bartolacci V, Bisio F, Riva A, Biassoni R, Moretta L, De Maria A. Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11970-5. doi: 10.1073/pnas.1302090110. Epub 2013 Jul 1
  4. De Maria A, Bozzano F, Cantoni C, Moretta L. Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16+ NK cells as rapid producers of abundant IFN-gamma on activation. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):728-32. Epub 2010 Dec 27.

Immunoregolazione

  1. Vacca P, Montaldo E, Croxatto D, Loiacono F, Canegallo F, Venturini PL, Moretta L, Mingari MC. Identification of diverse innate lymphoid cells in human decidua. Mucosal Immunol. 2015 Mar;8(2):254-64. doi: 10.1038/mi.2014.63. Epub 2014 Jul 23. PMID: 25052762
  2. Montaldo E, Teixeira-Alves LG, Glatzer T, Durek P, Stervbo U, Hamann W, Babic M, Paclik D, Stölzel K, Gröne J, Lozza L, Juelke K, Matzmohr N, Loiacono F, Petronelli F, Huntington ND, Moretta L, Mingari MC, Romagnani C. Human RORγt(+)CD34(+) cells are lineage-specified progenitors of group 3 RORγt(+) innate lymphoid cells. Immunity. 2014 Dec 18;41(6):988-1000. doi: 10.1016/j.immuni.2014.11.010. Epub 2014 Nov 28. PMID: 25500367
  3. Grauwet K, Cantoni C, Parodi M, De Maria A, Devriendt B, Pende D, Moretta L, Vitale M, Favoreel HW.Modulation of CD112 by the alphaherpesvirus gD protein suppresses DNAM-1-dependent NK cell-mediated lysis of infected cells. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16118-23. doi: 10.1073/pnas.1409485111. Epub 2014 Oct 28. PMID: 25352670
  4. Pietra G, Manzini C, Rivara S, Vitale M, Cantoni C, Petretto A, Balsamo M, Conte R, Benelli R, Minghelli S, Solari N, Gualco M, Queirolo P, Moretta L, Mingari MC. Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity. Cancer Res. 2012 Mar 15;72(6):1407-15. doi: 10.1158/0008-5472.CAN-11-2544. Epub 2012 Jan 18. PMID: 22258454